CAS-MAP Pan Caspase (VAD-FMK) Near Infrared Real time Apoptosis Probe (in vivo)
Near infrared imaging probe for non-invasive imaging of apoptosis (pan caspase) detection
Pan Caspase (VAD-FMK) Near Infrared Imaging Probe
In vivo detection of apoptosis in mouse tumor model
In vivo imaging of cell death in RPE
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CAS-MAP™ near infrared (NIR) probe provides a convenient and sensitive means for detecting activated caspases in vivo. The probe utilizes the caspase family inhibitor VAD-FMK conjugated to a near IR dye (780-VAD-FMK) as a marker. 780-VAD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspases in apoptotic cells. Apoptosis can be imaged in vivo over a time course with the use of animal imaging systems.
