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CAS-MAP ProBo Caspase 3 (DEVD-FMK) Green Real time Apoptosis Probe (in vivo)
Green Fluorescent non-invasive imaging probe for in vivo detection of apoptosis (caspase-3)
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CAS-MAP™ 3 apoptosis probes utilizes the caspase family inhibitor DEVD-FMK conjugated to an green fluorescent label (DEVD-FMK). The Caspase 3 probe is cell permeable, nontoxic, and irreversibly binds to activated caspases in apoptotic cells. The probe is injected in vivo to non-invasively detect cell death.
The ProBo™ ultrabright green fluorescent probe is up to 17x brighter than traditional probes and less sensitive to photobleaching, which may be desirable for tissue microscopy.