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Caspase 3/7 Reagent Kit (100 tests)

The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules. Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits: A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD)…

Merck

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Average Rating 3.9

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Good to use and better results

 

Average Rating 4.0

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It used to measure activity using a caspase-specific inhibitor sequence linked to a fluorescent prob

The Caspase 3/7 Reagent Kit is used to detect the activity of caspase-3 and caspase-7, which are enzymes that play important roles in apoptosis (programmed cell death) These kits use different methods to detect caspase activity, so you may want to choose one that best fits your experimental needs. It is easy to used use and but this product is avarage in value of money.

Review Date: 24 Jul 2023 | Merck

Average Rating 3.7

Works well but expensive.

Review Date: 1 Jul 2011 | Merck

The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules.

Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits:
A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD); a fluoromethylketone moiety (FMK) that forms a covalent linkage with the active enzyme; and a carboxyfluorescein (FAM) reporter.

The nuclear DNA stain is also included in the assay to simultaneously evaluate membrane integrity and cell viability. For use with all instruments.

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