Chirascan™ Circular Dichroism Spectrometer
High Performance - Ready to Run
Chirascan™ Circular Dichroism Spectrometer
Chirascan Control Software
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Great results an important asset and imprescriptible for my work.
Proteins and peptides structure, chirality spectroscopy
Practical, easy to use for newcomers and students, even biology students... You get exact and reproducible results, very good cost-effective
Review Date: 9 Jun 2022 | Applied Photophysics Ltd
Easy to use for students and professionals as well.
Structure determination for biological materials
Easy to use for students and professionals as well.
Review Date: 21 May 2021 | Applied Photophysics Ltd
Critical for my research.
Circular dichroism - mainly peptides and proteins structure
Easy to use for newcomers, get good reproducible results.
Review Date: 21 Mar 2020 | Applied Photophysics Ltd
Great equiiment to check secondary folding.
Protein chatacterization
CD is very easy to use. Interchangable cuvettes holder will allow to scan very wide protein concentrations. Detector is tuned to 1150-160nm which is great if you want to use for kinetics . Sample holder can be temp controlled from 5-95C and will allow to check protein stabilitt/melting. Lamp is amazing and vary stable, the same goes with monochromator. Data is used in provided software which makes it easy to detect melting points. After care is great and team is very responsive to your needs. You will have to use purest nitrogen available 5.0 (99.999%) to take good care of the optics.
Review Date: 5 Apr 2019 | Applied Photophysics Ltd
Very good instrument - critical for my research and others.
Chiral spectroscopy
A very effective and easy to use instrument - the reults are reliable accuratte and reprocudible. It is a major asset in structure determination of organic-biologic samples, proteins and peptides, and also for several other research areas. A sturdy instrument, not prone to technical problems. It is used regularly.
Review Date: 23 Mar 2019 | Applied Photophysics Ltd
Very good service.
Analyze secondary structure of peptides
Service both via email and on-site was very quick, professional and helpful. All employees are very friendly and pleasant to work with.
Review Date: 1 May 2018 | Applied Photophysics Ltd
Suitable for studying chiral molecules of all types and sizes, this Chirascan CD spectrometer has featured in thousands of publications since its introduction in 2005. Often used to analyze biomolecules, Chirascan data contributes to a deeper understanding of biomolecular characteristics, mechanisms and interactions.
When sensitivity and accuracy are key, our Chirascan V100 model (formerly Chirascan-plus) ensures that researchers can get the most from every CD analysis.
More than α-helix and β sheet - Determine structural and thermodynamic properties
- Gain insight and detect changes in secondary and tertiary structure
- Determine response to thermal or chemical change
- Study folding and unfolding mechanisms
- Expand capabilities with dedicated Chirascan accessories
Ready to run
Chirascan systems are supplied with the features and accessories required for acquisition of high quality data from ‘day one’.
Component Highlights
Molecular Sieve, Activated Charcoal Filter
- Removes common gas impurities
Active Nitrogen Management System
- Regulates purge gas consumption
- Software-controlled
Air-Cooled Xenon Lamp
- Software-controlled
- Up-time recorded
Monochromator
- Dual polarizing prisms maximize light throughput
- Produces horizontally, linearly polarized monochromatic light
Photoelastic Modulator
- Converts horizontally polarized light into circularly polarized light. Alternates between left- and right-handed circular polarized light
Temperature-Controlled Sample Chamber
- Consistent analytical conditions
- Continuous temperature ramps
- Temperature measured directly in sample
Water Circulator
- Dissipates heat from sample chamber and sample storage Peltiers
Photomultiplier Detector
Cuvettes and Holders
- Selected for far- and near-UV CD analysis of biomolecules (single sample mode)
Control and analysis software
- Easily defined run parameters and store routine protocols
- Saves time with scheduled start-up/shutdown of lamp and N2 supply
- Fail-safe lamp switch-off if N2 flow drops
- Ensures O2-free conditions with N2 purge
- Recognizes flow cell to select optimal run/wash/dry protocol
