Chirascan™ V100 Circular Dichroism Spectrometer
When Sensitivity and Accuracy are Key
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Great to use!
Structural Biochemistry
Easy and efficient to use.
Review Date: 15 Nov 2021 | Applied Photophysics Ltd
Great results! Serves a lot of research groups.
CD spectroscopy
I get good results - the spectrometer is very accurate, robust and simple to use. Students can use it easily after basic training.
Review Date: 22 May 2020 | Applied Photophysics Ltd
The Chirascan V100 CD spectrometer is ideal for examining chiral molecules of all types and sizes. Its sensitivity and accuracy ensure that researchers acquire the most from every CD analysis, producing high-quality data that adds to a deeper understanding of biomolecular mechanisms, characteristics, and interactions.
More than α-helix and β-sheet - determine structural and thermodynamic properties
- Achieve maximum accuracy and sensitivity
- Define response to thermal or chemical change
- Gain insight and detect variations in secondary and tertiary structure
- Expand capabilities with dedicated Chirascan accessories
- Study folding and unfolding mechanisms
Ready to Run
The Chirascan systems are provided with the features and accessories needed for acquisition of superior quality data from ‘day one’.
Component Highlights:
Molecular Sieve, Activated Charcoal Filter
- Removes common gas impurities
Active Nitrogen Management System
- Software-controlled
- Controls purge gas consumption
Air-Cooled Xenon Lamp
- Up-time recorded
- Software-controlled
Monochromator
- Dual polarizing prisms maximize light throughput
- Generates horizontally, linearly polarized monochromatic light
Photoelastic Modulator
- Changes horizontally polarized light into circularly polarized light. Alternates between left- and right-handed circular polarized light
Temperature-Controlled Sample Chamber
- Continuous temperature ramps
- Consistent analytical conditions
- Temperature measured directly in sample
Water Circulator
- Dissipates heat from sample chamber and sample storage Peltiers
Avalanche Photodiode Detector
- Maximum sensitivity (high signal: noise)
Optics-Based, Multi-wavelength Calibration
- For CD accuracy
Cuvettes and Holders
- Selected for far- and near-UV CD analysis of biomolecules (single sample mode)
Control and Analysis Software
- Ensures O2-free conditions with N2 purge
- Saves time with scheduled start-up/shutdown of lamp and N2 supply
- Easily defined run parameters and store standard protocols
- Recognizes flow cell to select best run/wash/dry protocol
- Fail-safe lamp switch-off if N2 flow drops
Global Thermodynamic Analysis
- Obtain melting points and enthalpies from multi-wavelength, thermal denaturation experiments
