Chondroitinase ABC

Chondroitin Sulfate Proteoglycans (CSPGs) are involved in the inhibition of axon regeneration after various forms of damage to the Central Nervous System, including stroke and spinal cord injury. The enzyme Chondroitinase ABC (purified from Proteus vulgaris) degrades these CSPGs, and has been shown to promote functional recovery and neural regeneration in addition to its role as a tool in glycoanalysis.