CIMmultus™
CIMmultus ™ is the new and improved line of pre-packed chromatographic monolithic columns distinguished by large flow-through channels, designed for working with large proteins (IgG, IgM, PEGylated proteins), viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), VLPs and pDNA.
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Expensive, not robust.
Preparitive chromatography
The CIMmultus OH monolith is not a robust device. Process development scale devices (1mL) do not scale to the 8mL and 80mL devices. Different capacities are observed. The device cannot be regenerated well, and does not show robust performance after cleaning with sodium hydroxide. The devices are very expensive, and lack options in size as they get larger.
Review Date: 16 Jun 2020 | BIA Separations
CIMmultus™ is the new and improved line of pre-packed chromatographic monolithic columns distinguished by large flow-through channels, designed for working with large proteins (IgG, IgM, PEGylated proteins), viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), VLPs and pDNA. Due to their performance properties, CIMmultus™ columns can be used as single-use disposable or multi-use columns. An important feature of CIMmultus™ is its housing; made of epoxy thermoset materials and reinforced with carbon fibers, it gives the column the same structural strength as stainless steel. CIMmultus™ columns are cGMP compliant.
CIMmultus™ columns are available with 1.3μm, 2μm,and 6μm channels.
