CombiFlash NextGen 300+
The CombiFlash NextGen 300+ comes standard with all options installed. Flow rate range is from 1 to 300 mL/min at operating pressures up to 300 psi (20 bar). The system is fitted with a solid load injection valve that can be bypassed if you decide to perform a liquid injection.
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Great, easy to use instrument
Purification of small molecules
Extremely easy to use, minimal maintenance required. Nice availability of add-ons to make instrument more robust
Review Date: 28 Sept 2023 | Teledyne Labs
Easy to use and a huge timesaver!
Organic synthesis
Easy to use and importantly, easy to teach other people to use. Results are pretty good, though some compounds still separate better by hand. It saves so much time on easy separations though, that a system such as this one would be a valuable addition to any lab.
Review Date: 26 Sept 2023 | Teledyne Labs
Great, this instrument is vital for us
Purification of compounds for chemistry
The reproductibility of the instrument and cartridges is very good and help us a lot to maintain a goood productivity in tha lab. Also the representative from Teledyne is coming often in the lab to check up with us and give us some updates on the new product that you are selling which is also nice!
Review Date: 26 Sept 2023 | Teledyne Labs
Ease of use and short learning curve. Helpful seminar series.
Purification
Used flash chromatography for large purification of oligonucleotides with phosphonamidite. Ease of use for a beginner. Also their seminar series are helpful.
Review Date: 26 Sept 2023 | Teledyne Labs
Great results, very easy to use and highly reliable & big asset to the R&D program.
Purify flash chromatography of chemical small molecules.
This instrument if highly effective and very easy to use. The maintains cost for this instrument is literally zero if you use this instrument properly on day-to-day basis. Would recommend and must have for Discovery research group.
Review Date: 26 Sept 2023 | Teledyne Labs
Since I have been using it, I cannot imagine doing manual column chromatography again
Purification of bioactive small molecules
The machine is easy to use and reliable. It allows for reproducible purification. Rarely, either hardware or software bugs appear which are often difficult to fix, but it is considered normal given the heavy usage of the equipment in our laboratory. Generally the support is prompt and helpful. We have several of these machines in our laboratory and it was always a good experience working with them. It significantly improves our group's productivity allowing for the discovery of novel antimicrobial compounds at a faster rate.
Review Date: 25 Sept 2023 | Teledyne Labs
Great Results
Sample purification
Easy to use and effective purifications
Review Date: 25 Sept 2023 | Teledyne Labs
Easy to use flash chromatography
Pharma
Easy to use and one page software, remote control possible, we have lot of them in use as well as in openaccess mode, NP and RP possible with one model
Review Date: 25 Sept 2023 | Teledyne Labs
Have great results by using this instrument. Can't live and work without it. :)
Purification small molecules building blocks and final compounds
I'm using Combi Flash system for many years (~8-9) and this new system is very well design to maintain, easy to transfer purification method from TLC analysis. The system maintains consistently in pressure and fraction collection for using the same method for similar analogues. It's easy to change method during ongoing purification while developing new method for analogues purification. I like options to extend the run without finishing it, change solvent % during run. Also, I like the option of monitoring purification with different UV absorption running simultaneously. Additionally, I'm very pleased with the size of the instrument itself. In many labs researchers doesn't have extra space to put very useful instrument. especially under the hood, because of dangerous vapors of many solvents. The Combi Flash Nextgen 300+ is very compact and you can have a cover for racks to avoid vapors getting out and can keep the instrument on the open bench space in the lab. The maintenance of this Combi Flash also is very easy and Teledyne ISCO technician (I would like especially mention Nancy Fowler) helped a lot in method transfer and answered all questions about method design, some tips and tricks in use and maintenance.
Review Date: 25 Sept 2023 | Teledyne Labs
Easy chromatography!
Organic Chemistry Purification
Fast and easy chromatography; maintenance on system is simple. Only downside is that the columns are costly
Review Date: 25 Sept 2023 | Teledyne Labs
The CombiFlash NextGen 300+ comes standard with all options installed. Flow rate range is from 1 to 300 mL/min at operating pressures up to 300 psi (20 bar). The system is fitted with a solid load injection valve that can be bypassed if you decide to perform a liquid injection. RFID technology comes standard and automatically reads the size and type of RediSep or RediSep Gold column being used for the purification. Based on this information, a default gradient and flow rate are programmed into the system. Simply insert the column into the stand, press Play and the run starts. This same RFID technology automatically reads the rack type being used ensuring there is never a missed or overfilled tube. Active solvent and waste level monitoring is standard on the NextGen 300+.
