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COVID-19 Spike-ACE2 Binding Assay Kit

The RayBio® COVID-19 Spike-ACE2 binding assay kit is a rapid, simple, and sensitive method to characterize the binding affinity of the SARS-CoV-2 Spike (S) protein and the Angiotensin I Converting Enzyme 2 (ACE2) receptor complex in the presence of potential inhibitors.

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RayBiotech Inc.

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Note:

The binding assay comes in two different options based on which protein is immobilized on the plate and which protein is added in solution (i.e. "query"). It is the researcher's responsibility to select the format for their study.

Antigen InformationAccession Number:

QHD43416

Gene Symbols:

ACE2; RBD; S; S-RBD; SRBD

Protein Name & Synonyms:

Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15, Processed angiotensin-converting enzyme 2, ACE2, Spike protein, S Protein, S1 Subunit, Host Cell Receptor Binding Domain (RBD)

Assay FormatNumber of Targets Detected:

1

Species Detected:

Human; SARS-CoV-2

Compatible Sample Types:

Antibodies; Peptides; Plasma; Proteins; Serum; Small Molecules

Method of Detection:

Colorimetric

Quantitative/Semi-Quantitative:

Semi-Quantitative

Solid Support:

96-well Microplate

Product SpecificationsSize:

1, 2, or 5 x 96-Well Strip Microplate Kit

Validation DataInhibition of Spike-ACE2 by anti-viral compoundsInhibition of Spike-ACE2 by anti-Spike antibodiesApplication Notes

  • Evaluate inhibitor activity
  • Screen inhibitors of the SARS-CoV-2 Spike-ACE2 complex
  • Characterize antibody function
  • Vaccine development
  • Selection of patient serum for antibody therapy

Storage/Stability

Store kit at 4°C for up to 6 months from date of shipment.

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