Products & ReviewLife Sciences
Dexamethasone
Glucocorticoid pathway activator; Activates glucocorticoid receptor
Dexamethasone
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Dexamethasone is a synthetic glucocorticoid, similar to the natural glucocorticoid hydrocortisone. Dexamethasone has an increased affinity for glucocorticoid receptors when compared to the natural hydrocortisone ligand (Kd = 5 nM vs 17 nM).
REPROGRAMMING
- Promotes transdifferentiation of hepatocytes from mouse pancreatic cells (Shen et al.).
DIFFERENTIATION
- Promotes osteogenic, adipogenic, and chondrogenic differentiation of human mesenchymal cells (Jaiswal et al., Mackay et al., Pittenger et al.).
- Promotes osteogenic, adipogenic, and chondrogenic differentiation of mouse mesenchymal cells (Tropel et al.).
- Promotes differentiation of mature hepatocytes from mouse and human embryonic stem (ES) cells (Cai et al., Kubo et al.).
- Promotes maturation of fetal mouse hepatocytes (Kamiya et al.).
