DNMT Activity / Inhibition Assay
Highly sensitive and rapid microplate-based assay to simplify the measurement of DNA methyltransferase activity
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
The DNMT Activity / Inhibition Assay is a non-radioactive assay to measure the activity or inhibition of DNA methyltransferases.
The sensitive ELISA-based method utililzes the high affinity binding of methyl CpG binding domain (MBD) protein towards methylated DNA in order to detect DNA methyltransferase activity on the provided CpG-enriched DNA substrate. The assay is performed in a 96-stripwell plate, enabling low or high throughput screening that is easily quantified by spectrophotometry.The DNMT Activity / Inhibition Assay provides everything needed to study DNA methyltransferase activity from recombinant DNMT enzymes (DNMT1, DNMT3a & DNMT3b) or nuclear extract samples. A CpG Methyltransferase is included as a positive control.