Products & ReviewLife Sciences
Fluoxetine
Serotonin reuptake inhibitor
Fluoxetine (Hydrochloride)
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Fluoxetine is a selective serotonin reuptake inhibitor, displaying a distinct preference for the serotonin transporter (Kd = 0.81 nM) over both the norepinephrine and dopamine transporters (Kd values of 240 and 3600 nM, respectively; Tatsumi et al.). This product is supplied as a hydrochloride salt of the molecule.
DIFFERENTIATION
- Induces proliferation of human embryonic stem cell-derived neural precursors, and enhances their neuronal differentiation (Chang et al. 2010).
MAINTENANCE
- Induces proliferation and inhibits differentiation of human hypothalamic neuroprogenitor cells (Sousa-Ferreira et al.).
- Stimulates proliferation of mouse fetal neural stem cells (Chang et al. 2012).
- Stimulates in vivo proliferation of amplifying neural progenitor cells in adult mouse brain (Encinas et al.).
