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FormaPure RNA

RNA Isolation from FFPE Tissue

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Beckman Coulter Life Sciences

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Agencourt FormaPure RNA provides a simple, automation-friendly process for extracting RNA from formalin-fixed, paraffin-embedded (FFPE) tissue samples. By utilizing the Solid Phase Reversible Immobilization (SPRI) paramagnetic bead-based technology, Agencourt FormaPure RNA does not require vacuum filtration, centrifugation, or organic solvents such as phenol or xylene. Researchers can go from paraffin digestion to total nucleic acid extraction in about four hours (without setup) for 96 samples in a multi-well format utilizing a Biomek liquid handler. Recoveries are consistently higher than competitive techniques.

FormaPure RNA is one of three reagent kits in the FormaPure family, which also includes FormaPure Total for total nucleic acid isolation and FormaPure DNA for DNA isolation. FormaPure reagent kits are a single chemistry system designed and optimized for use in next-generation sequencing (NGS) and other downstream applications including qPCR/ddPCR/PCR.

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