Products & ReviewLife Sciences

Gibco™ CTS™ TrypLE™ Select Enzyme

Thermo Fisher ScientificA4738001Available: Worldwide

Recombinant enzyme capable of dissociating a wide range of adherent mammalian cells

Thermo Fisher Scientific

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CTS TrypLE Select Enzyme is derived from microbial fermentation and provides an animal origin free (AOF) alternative to porcine trypsin. Compared to other dissociation reagents, CTS TrypLE Select Enzyme is:

  • Animal origin-free (AOF)—free of animal-derived components and formulated on dedicated animal origin-free equipment. CTS TrypLE Select Enzyme reduces risk of viral or prion contamination in your clinical manufacturing.
  • Gentle on cells—CTS TrypLE Select Enzyme's exceptional purity increases specificity due to the action of a single enzyme. This reduces damage caused by cleavage from multiple enzymes in trypsin and other extracts.
  • Room temperature-stable—Product remains stable at room temperature or 2–8°C, making storage and handling easy and convenient.
  • Easy to use—CTS TrypLE Select substitutes directly into existing protocols, with no inactivation required avoiding the need for trypsin inhibitors, such as FBS.

The product is provided as a 1X stock solution, formulated in DPBS with 1 mM EDTA. Gibco CTS products are designed for use in manufacturing of cell or gene products, supporting your transition from research to clinical applications. Closed systems compatible The 1-liter size of CTS TrypLE Select Enzyme is provided in bioprocess container format with the chamber constructed from Aegis 5-14 film. Sterile, weldable C-Flex tubing with female luer lock provides versatile connection options for integrating into a closed system manufacturing process.

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