Gibco™ Geltrex™ Reduced Growth Factor Basement Membrane Matrix

Gibco Geltrex™ matrix is a soluble form of reduced growth factor (RGF) basement membrane extract (BME) purified from continuous sheets of specialized extracellular matrix that form an interface between Engelbreth-Holm-Swarm (EHS) tumor cells. The major components of Geltrex™ matrix include laminin, collagen IV, entactin, and heparin sulfate proteoglycan, which provide the foundation for three-dimensional (3D) culture studies. Like naturally occurring basement membrane, Geltrex™ reduced growth factor basement membrane not only supports cells and cell layers, but also plays an essential role in tissue organization that affects cell adhesion, migration, proliferation, and differentiation. Features include: 3D extracellular matrix that mimics in vivo conditions Reduced growth factor content and protein specification ensure lot consistency Suitable for a broad range of applications Functional testing on each lot