GrowDex® syringe (5 ml) + GrowDase™ (2.5 ml) combo pack
GrowDex® hydrogel consists of nanofibrillar cellulose (1.5% w/v) and 98.5% purified water and is supplied ready to use. GrowDex is ready to use and can be mixed directly with cells and culture media, no gelation or cross-linking step required. Ambient handling and shear thinning properties of GrowDex enable easy dispensing and use in automated systems. Please refer to the product Instructions for Use and the Quickstart Guide a…
Evaluation of transduction efficiency in a 3D in vitro model
The service of UPM is very efficient: quick delivery (in UK at least), comprehensive process of discussion with a representative to optimise your study, availability for meetings if necessary, reactivity. The products (both GrowDex and GrowDase) are very easy to use with only one exception: the step of changing the media (manually) which can induce some variability in your final results. To fix this issue, we had discussions with UPM and they proposed some solution including the use of automated liquid handlers. Overall, the repeatability of my experiments was acceptable (<20% CV, N=6). The generation of spheroids was slightly different according to the cells type I was using, but the generation happened in any case (1 ipsc-derived cell, 1 primary cell, 2 cell lines). GrowDase is absolutely straight forward to use. I will keep using Growdex for my future works involving the use of an in vitro 3D model.
Review Date: 19 Jan 2022 | UPM Biomedicals
Cell culture
The quality of the product is extremely high. It is easy to store even at room temperature. It is easy to repeat the results since the product is stable. We can open and close the syringe, and use all the material to the list drop during a long time period even two - to - three years, and no changes occur. So extremely great product for cell culture. We have obtained a new types of systems and data, and are still actively working with the GD and GD.
Review Date: 8 Dec 2021 | UPM Biomedicals
With GrowDex® hydrogels you can work through your entire HTS/HCS workflow form setting up your assays, screening your compounds, analysing your cells and moving to downstream processes, with high biological predictability and reproducibility, while saving time and costs.
- Simple & Customisable - Our biocompatible hydrogels are made from just 2 components, nanofibrillar cellulose and purified water. They can be customised easily by simply adding components such as growth factors or proteins directly to the gel. Stiffness of the gel is achieved by dilution the your cell media.
- Convenient & Easy to Use - All our hydrogels are provided ready to use in handy syringes for easy handling and dispensing and can be stored at ambient temperature. No cross-linking, gelation or sonication steps are required, just mix the hydrogel with your media and cells, dispense and incubate. Cells or organoids can be recovered using GrowDase in a one-step process without harm from mechanical damage.
- Reliable & Reproducible - Our hydrogels are manufactured to the highest standards and their performance measured against strict quality control criteria, so you can be sure the performance will be the same regardless of the Lot ordered. The hydrogels are not autofluorescent so imaging with any microscope or high content imaging system is simple and the ambient handling of the hydrogels makes them ideal for high throughput assays.
Applications for GrowDex® Hydrogels:
- 3D cell culture for spheroid, organoids and biopsy cultures
- High-Throughput Screening
- High-Content Screening
- Transportation and storage of cells
- Regenerative medicine
- Cell therapy
- Organ-on-a-chip models
- Drug release studies
- Bioprocessing