Human Nav1.2 Sodium Channel Division-Arrested Cells
The human Nav1.2 gene encodes the pore-forming subunit of voltage-gated type-2 Na+ channels. Neuronal Nav1.2 channels are therapeutic targets in seizure, pain, and stroke. Synonyms: brain type-2 sodium channel Host cell: CHO-K1 Gene name: SCN2A Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cyropreserved irradiated cells, 2 x 106 cells/vial (6x106 cells total) Growth media: Ham’s F12; 10% FBS Growth cha…
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The human Nav1.2 gene encodes the pore-forming subunit of voltage-gated type-2 Na+ channels. Neuronal Nav1.2 channels are therapeutic targets in seizure, pain, and stroke.
Synonyms: brain type-2 sodium channel
Host cell: CHO-K1
Gene name: SCN2A
Mycoplasma status: Negative (MycoAlert Kit)
Packaging: Three vials of Cyropreserved irradiated cells, 2 x 106 cells/vial (6x106 cells
total)
Growth media: Ham’s F12; 10% FBS
Growth characteristics: cells remain viable 1–2 days post-thaw
Storage recommendation: frozen under liquid nitrogen
Functional expression: median Na+ current amplitude = 0.84 nA
Recommended assays: manual or automated patch clamp
