Human Nav1.4 Sodium Channel EZCells

Name: Human Nav1.4 Sodium Channel EZCells
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The SCN4A gene encodes the pore-forming subunit of the voltage-gated, skeletal muscle Na+ channel. Nav1.4 is a therapeutic target for treatment of myotonia. Synonyms: Skeletal muscle sodium channel, SkM1 Host cell: CHO-K1, division-arrested Gene name: SCN4A Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cryopreserved irradiated cells, 2x106 cells/vial (6x106 cells total) Growth media: Ham’s F12; 10% FBS…

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The SCN4A gene encodes the pore-forming subunit of the voltage-gated, skeletal muscle Na+ channel. Nav1.4 is a therapeutic target for treatment of myotonia.

Synonyms: Skeletal muscle sodium channel, SkM1
Host cell: CHO-K1, division-arrested
Gene name: SCN4A
Mycoplasma status: Negative (MycoAlert Kit)
Packaging: Three vials of Cryopreserved irradiated cells, 2x106 cells/vial (6x106 cells
total)
Growth media: Ham’s F12; 10% FBS
Growth characteristics: cells remain viable 1–2 days post-thaw
Storage recommendation: frozen under liquid nitrogen
Functional expression: median Na+ current amplitude = 1.8 nA
Recommended assays: manual or automated patch clamp