Human Nav1.5 Sodium Channel Division-Arrested Cells
The human Nav1.5 gene encodes the pore-forming subunit of the voltage-gated, cardiac Na+ channel. Nav1.5 is an antiarrhythmic therapeutic target. Synonyms: cardiac sodium channel Host cell: CHO-K1 Gene name: SCN5A Mycoplasma status: Negative (MycoAlert Kit) Packaging: Three vials of Cyropreserved irradiated cells, 2 x 106 cells/vial (6x106 cells total) Growth media: Ham’s F12; 10% FBS Growth characteristics: cells remain viab…
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The human Nav1.5 gene encodes the pore-forming subunit of the voltage-gated, cardiac Na+ channel. Nav1.5 is an antiarrhythmic therapeutic target.
Synonyms: cardiac sodium channel
Host cell: CHO-K1
Gene name: SCN5A
Mycoplasma status: Negative (MycoAlert Kit)
Packaging: Three vials of Cyropreserved irradiated cells, 2 x 106 cells/vial (6x106 cells
total)
Growth media: Ham’s F12; 10% FBS
Growth characteristics: cells remain viable 1–2 days post-thaw
Storage recommendation: frozen under liquid nitrogen
Functional expression: median Na+ current amplitude = 2.42 nA
Recommended assays: manual or automated patch clamp