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Human Recombinant MCP-2 (CCL8)
Monocyte chemoattractant protein 2
Human Recombinant MCP-2 (CCL8)
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Monocyte chemoattractant protein (MCP) 2, or CCL8, belongs to the MCP subgroup of the CC family of chemokines, which includes MCP-1, MCP-2, MCP-3, MCP-4, and MCP-5. MCP-2 signals primarily through the CCR1 and CCR5 receptors to attract monocytes, activated NK cells, and CD4+ and CD8+ T cells (Romagnani). MCP-2 has also been shown to induce the release of histamine from basophils via the CCR2 receptor (Gangur & Oppenheim).
