Products & ReviewLife Sciences
ID-8
DYRK pathway inhibitor
ID-8
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ID-8 is an indole derivative (Miyabayashi et al.) that inhibits members of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family (Hasegawa et al.).
MAINTENANCE AND SELF-RENEWAL
- Enables maintenance of mouse embryonic stem (ES) cells in the absence of mouse embryonic fibroblast (MEF) feeder cells, serum, or LIF (Miyabayashi et al.).
- In combination with Wnt, supports human ES cell proliferation and survival, without FGF or TGFβ (Hasegawa et al.).
