In Vitro ADMET Services
At Peakdale we offer a range of in vitro ADMET predictive models, delivering accurate and reproducible data, maintaining a focus on efficient turnaround times to facilitate our customers' drug discovery programs. In addition to our core assays, we also offer our clients the flexibility of bespoke assay design. The majority of our assays utilise sensitive "state of the art" triple quad LC-MS/MS ESI detection. Complementing our…
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At Peakdale we offer a range of in vitro ADMET predictive models, delivering accurate and reproducible data, maintaining a focus on efficient turnaround times to facilitate our customers' drug discovery programs.
In addition to our core assays, we also offer our clients the flexibility of bespoke assay design. The majority of our assays utilise sensitive "state of the art" triple quad LC-MS/MS ESI detection.
Complementing our laboratory facilities, we have an in silico capability dedicated to virtual high throughput screening, optimising ADMET properties to aid rational compound selection for in vitro experiments.
We support our clients with results interpretation and direct communication with our assay experts.
Features:
- Solubility
- Lipophilicity
- Permeability
- Plasma protein binding
- Metabolic stability
- CYP450 metabolic inhibition
- CYP induction
- Cytotoxicity
- In silico modelling
- Customer specific assays
