Inertsil Hybrid-C18 LC Column

Inertsil Hybrid-C18: A Durable Reversed-Phase Column for High-pH Applications

GL Sciences introduces Inertsil Hybrid-C18, an advanced reversed-phase HPLC column that combines the robustness of hybrid silica technology with the reliability required for high-performance analytical workflows. Designed for laboratories that routinely handle basic compounds or operate under harsh mobile phase conditions, this column offers long-lasting durability and excellent chromatographic performance across a wide pH range.

Unlike conventional silica-based C18 columns, which can degrade under alkaline conditions, Inertsil Hybrid-C18 maintains high efficiency and peak shape integrity even at pH levels up to 12. This makes it a powerful tool for LC-MS, peptide separations, pharmaceutical analyses, and other applications requiring chemical stability and reproducibility.

Key Features of Inertsil Hybrid-C18:

• Wide usable pH range: 1–12
• High alkali resistance using hybrid silica particles
• Excellent peak shape for basic and polar compounds
• Improved column lifetime under high-pH conditions
• Suitable for LC-MS and UHPLC applications
• Available in 1.7 µm, 3.5 µm, and 5 µm particle sizes
• Reproducible results for regulated environments and method validation

Inertsil Hybrid-C18 is ideal for laboratories seeking a rugged, high-performance solution to overcome the limitations of standard reversed-phase columns. It is particularly useful in pharmaceutical, environmental, and bioanalytical workflows where column stability and data consistency are essential.

For further details and ordering information, visit www.glsciences.com