ioGlutamatergic Neurons human iPSC derived glutamatergic neurons
A highly defined, scalable, and consistent source of human central nervous system (CNS) neurons. ioGlutamatergic Neurons, part of the bit.bio ioCells portfolio, are reprogrammed from human induced pluripotent stem cells (iPSC) using bit.bio's precise reprogramming technology: opti-ox™ (optimised inducible overexpression).
Cell culture of human induced glutamatergic neurons
I am a research associate at the University of Cambridge studying neuronal and glial cells. I have been using these neurons from bit.bio for more than a year now for several applications such as 2D and 3D tissue cultures (in vitro disease modeling), RNA-sequencing, western blot, electrophysiology recordings and etc. These cells provide a reliable and pure source of glutamatergic neurons, resembling primary human ones. They are ready-to-use which makes it much more easy for tissue culture work and for reproducible results. I haven't encounter any special issues with this cell line and the company has been very helpful providing me with all necessary information to establish my work. I highly recommend their iPSCs derived neurons as a good source of cells for neuroscience research.
Review Date: 21 Apr 2020 | bit.bio
bit.bio’s opti-ox™ cellular reprogramming enables the consistent manufacture of homogenous and mature hiPSCs derived functional neurons within days, offering access to the highest quality cellular CNS model with simple protocols.
ioGlutamatergic Neurons cells provide you with:
- Consistency: Batch-to-batch reproducibility and homogeneity create a stable human model for excitatory neuronal activity and disease
- Speed: Ready for experimentation as early as two days post revival and form functional neuronal networks at 17 days
- Scalability: Industrial-scale quantities allow the cells to be used in a range of applications, from research to screening purposes
- Ease of Use: Cells arrive programmed to rapidly mature upon revival with only one medium required in a two-step protocol