Products & ReviewLife Sciences
L755507
Activates ß-3 adrenergic receptors
L755507
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L755507 is a potent and selective β-3 adrenergic receptor agonist that demonstrates > 440-fold selectivity over β-1 and β-2 binding (EC50 = 0.43, 580, and > 10,000 nM for activation of cloned human β-3-, β-2-, and β-1-adrenoreceptors, respectively; Parmee et al.).
DIFFERENTIATION
- Stimulates lipolysis in human white adipose tissue (Fisher et al.).
GENE EDITING
- Improves the efficiency of homology-directed repair in human induced-pluripotent stem cells following CRISPR editing (Yu et al.).
METABOLISM
- Increases metabolism in rhesus monkeys (Fisher et al.).
