Lead Optimization Pharmacology Service
Capitalize on the intricacies of research questions honed over thousands and thousands of in vivo pharmacology studies conducted by Covance. Procure Covance's in vivo pharmacology expertise and capabilities for your benefit in the design, validation, conduct, and analysis of animal efficacy pharmacology studies for your drug candidates.Lead Optimization Pharmacology Service Features: Assessing and engaging the target tiss…
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Capitalize on the intricacies of research questions honed over thousands and thousands of in vivo pharmacology studies conducted by Covance.
Procure Covance's in vivo pharmacology expertise and capabilities for your benefit in the design, validation, conduct, and analysis of animal efficacy pharmacology studies for your drug candidates.
Lead Optimization Pharmacology Service Features:
- Assessing and engaging the target tissues (Exposure/Receptor Occupancy)
- Modulating target activity (Pharmacodynamic/ disease markers)
- Pharmacological efficacy
- Selective engagement of target (Selectivity)
- Comparisons to reference compounds and structural analogs (Optimization)
- Side effects/adverse effects
