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LightSwitch™ miRNA Target Validation Services

Full screening service to validate the 3´UTR targets of specific miRNAs

Active Motif

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Identifying the mRNA targets of a miRNA in any given cell type remains a significant challenge.

Computational predictions are not accurate and require validation while transcript-based expression analysis cannot measure the functional role of miRNAs. Active Motif's luciferase-based 3´UTR reporter screening service has the ability to measure actual miRNA function. Our miRNA Target Validation Services enable you to identify functional miRNA targets, compare luciferase data with endogenous transcript and protein levels, characterize dose responsiveness of luciferase reporters and verify specificity of miRNA / reporter interactions.

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