LightSwitch™ Promoter Reporter GoClone™ Collection
For use with The LightSwitch™ Luciferase Assay System for analysis of promoter regulation
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
The LightSwitch Luciferase Assay System and Promoter Reporter Collection are important tools for determining how a transcription factor regulates its target genes.
Researchers can monitor changes in any promoter's activity in response to variations in transcription factor function that may be modulated by techniques like over-expression, knock-down or treatment with a known agonist or antagonist. LightSwitch Promoter Reporter constructs are also useful for assessing the functional consequences of transcription factor binding detected through a ChIP-based experiment and for measuring the effects of mutagenizing a putative transcription factor binding motif.
Applications:
- Monitoring changes in promoter activity in response to variations in transcription factor function.
- Assessing the functional consequences of transcription factor binding detected through a ChIP-based experiment.
- Measuring the effects of mutagenizing a putative transcription factor binding motif.
- Verifying computational predictions and supplementing microarray or Next-Generation sequencing data.