MCF-7
Human Breast Adenocarcinoma cell line. Frozen cryovial. 2 Mio. cells/ml.
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Organism: Homo sapiens (human)
Ethnicity: Caucasian
Age: 69 years old
Gender: female
Tissue: Breast
Morphology: Epithelial-like
Celltype: Adenocarcinoma
Growth Properties: monolayer, adherent
Description: The MCF-7 cell line was established from the pleural effusion of a patient suffering from a breast adenocarcinoma. It retains several characteristics of differentiated mammary epithelium including the ability to process estradiol via cytoplasmic estrogen receptors and the capability of forming domes. Growth of MCF-7 cells is inhibited by tumor necrosis factor alpha (TNF alpha). Secretion of IGFBP's can be modulated by treatment with anti-estrogens.
