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Microglial Cell Line (IMG)
KerafastAvailable: Worldwide
Immortalized microglial cell line (IMG) isolated from the brains of adult mice
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Immortalized microglial cell line (IMG) isolated from the brains of adult mice.
Highlights:
- Express the markers F4/80 and CD11b but not the neuronal marker NeuN or the astrocyte marker GFAP
- Display a robust response (M1/M2 polarization) to inflammatory signals and can therefore be used to examine mechanisms of drug action and drug efficacy in regards to M1/M2 polarization
- Can be induced to pro- or anti-inflammatory microglial phenotypes *Able to phagocytose foreign particles and misfolded proteins such as amyloid-beta peptide
