Monastrol
A potent, cell permeable, non-tubulin-interacting mitosis inhibitor. Arrests mammalian cells in mitosis with monopolar spindles. In vitro it specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein involved in the assemble and maintainance of the mitotic spindle.
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efficient and effective inhibitor of kinesin-5.
Review Date: 17 Jan 2011 | Merck
A potent, cell permeable, non-tubulin-interacting mitosis inhibitor. Arrests mammalian cells in mitosis with monopolar spindles. In vitro it specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein involved in the assemble and maintainance of the mitotic spindle.
