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NeuroCult™ SM1 Neuronal Supplement

Supplement for the serum-free culture of primary tissue-derived neurons and hPSC-derived neural progenitor cells

STEMCELL Technologies Inc.

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NeuroCult™ SM1 (STEMCELL Modified-1) Neuronal Supplement is a standardized serum-free supplement for the culture of primary tissue-derived neurons and human pluripotent stem cell (hPSC)-derived neural progenitor cells.

The NeuroCult™ SM1 formulation was developed based on the published formulation of Brewer’s B27 supplement (Brewer et al.). It has been optimized to reproducibly support increased survival and maturation of functional neurons in both short- and long-term cultures with minimal glial cell contamination (< 1% GFAP+). NeuroCult™ SM1 may be used in combination with BrainPhys™ Neuronal Medium (Catalog #05790) or as a serum-replacement supplement for various customizable applications.

NeuroCult™ SM1 is also a component of BrainPhys™ Neuronal Medium and SM1 Kit (Catalog #05792), BrainPhys™ Neuronal Medium N2-A & SM1 Kit (Catalog #05793), and BrainPhys™ Primary Neuron Kit (Catalog #05794). For further details and protocols, refer to the Product Information Sheet (PIS) for BrainPhys™ (Document #DX20519), available at www.stemcell.com or contact us to request a copy.

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