Oligonucleotide Synthesis Materials

Stable isotope labeling is a powerful tool utilized in nucleic acid research, enabling detailed investigations of oligonucleotide structure, dynamics and function utilizing methods like nuclear magnetic resonance (NMR) and mass spectrometry (MS). The incorporation of stable isotopes such as 13C, 15N, and 2H into RNA or DNA enables the determination of detailed mechanistic insights and interactions, enhances analytical performance, and even enables quantification. CIL offers a comprehensive product portfolio of high-quality, stable isotope-labeled RNA and DNA building blocks designed for both enzymatic and chemical synthesis approaches.