Parallel Pressure Reactor

An automated platform for parallel synthesis and polymerization studies over a range of controlled temperatures and pressures in the chemicals and pharmaceuticals laboratory

The modular PPR, with hardware and software capabilities, provides a fully automated robotic platform in which up to 48 isolated reactions can be conducted in parallel. The system enables a scientist to design experiments, execute syntheses, monitor conversion, and analyze data in one complete system.

By enabling higher throughput and automation, less experimentation time is needed and greater experiment-to-experiment reproducibility is achieved. This platform extends the capabilities of a scientist and a research team to explore a far broader range of reactions, catalysts, and reaction conditions than is possible using conventional methods.

Prepare: Modularized for flexibility in experimentation

• Robotic preparation. Design and automation software work together to allow the robotic system to interpret a recipe containing composition and process information and prepare stock solutions, dispense materials to the array of reactors, and set the reaction conditions.
• Injection under pressure. Liquids or slurries can be injected at pressure into the reactor cells to start or quench a reaction under the designed conditions.

Process: Complete automation for faster time to result

• Operation in isolated environment. The reactor and liquid handling robot are integrated into a triple-section glove box to enable studies of air-sensitive chemistry.
• Individual experiment control. Each 8-cell module has pressure and temperature control allowing a diversity of reaction conditions to be explored simultaneously.
• Reaction monitoring. Each cell is monitored for gas uptake in real time allowing per reaction conversion measurement. Such real-time monitoring allows polymerization reactions to be quenched at a common conversion.

Analyze: Multi-dimensional experimentation for better data correlation

• Enables rapid analysis. Being able to query data by parameters such as compound name, structure, reaction conditions and conversion provides a facile way to manage hundreds of experiments across a campaign.
• Storage of data on an applications database. Allows for sharing of experiments across internal and external labs.