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PhIP-Seq

VirScan™, HuScan ® , and MouseScan™ are applications of bacteriophage-display immunoprecipitation sequencing (PhIP-Seq), a powerful method of multiplexed analysis that combines high-throughput DNA sequencing with next-generation proteomics. PhIP-Seq is the highest-coverage antigen-specific assay yet developed, able to detect antibodies versus virtually any antigen via overlapping peptides.

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VirScan™, HuScan®, and MouseScan™ are applications of bacteriophage-display immunoprecipitation sequencing (PhIP-Seq), a powerful method of multiplexed analysis that combines high-throughput DNA sequencing with next-generation proteomics. PhIP-Seq is the highest-coverage antigen-specific assay yet developed, able to detect antibodies versus virtually any antigen via overlapping peptides.
VirScan* allows researchers to determine what antibodies were created by an individual’s unique history of viral exposures. The VirScan PhIP-Seq library is designed to identify IgG antibodies versus viral protein sequences from most known proteins from human, mammalian, other vertebrate, mosquito-borne, tick-borne, and other viral genomes.
HuScan* allows for epitope-level antibody discovery against the entire human proteome. The HuScan service enables the analysis of patient samples (serum, plasma, CSF, etc.) for the presence of autoantibodies against a full RefSeq human proteome in a single-well assay with quantitative sequencing readouts.
MouseScan* allows for epitope-level antibody discovery against the entire murine proteome. The MouseScan service enables the analysis of preclinical murine samples for the presence of autoantibodies against the full GRCm38.p5 mouse proteome in a single-well assay with quantitative sequencing readouts.
* VirScan, HuScan and MouseScan are provided exclusively by CDI Labs Canada.

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