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PL-SAX for Prep to Process

Agilent TechnologiesAvailable: Worldwide

PL-SAX strong anion-exchange materials are extremely hydrophilic and are designed for purification of biomolecules. The materials are totally polymeric and are chemically and thermally stable over a full range of HPLC conditions.

Agilent Technologies

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PL-SAX strong anion-exchange materials are extremely hydrophilic and are designed for purification of biomolecules. The materials are totally polymeric and are chemically and thermally stable over a full range of HPLC conditions.

The strong anion-exchange functionalities, covalently linked to a chemically stable polymer, facilitate anion-exchange purifications over a wider pH range. This stability can be exploited for column sanitation and clean-up, and also enables the use of denaturing conditions and stabilizing/solubilizing agents, as encountered in the purification of synthetic oligonucleotides with self-complementary sequences.

Features:

  • Anion-exchange purifications over a wider pH range extend applications
  • HPLC flow rates and rapid equilibration reduce purification cycle times
  • Large pore size for improved mass transfer delivers high speed, high resolution purifications
  • 1000Å pore size for high capacity purifications
  • 4000Å gigaporous particles with improved mass transfer for large biomolecules and high-speed, high-resolution purifications

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