Primary Screening with CETSA
Primary screening based on Cellular Thermal Shift Assay (CETSA) allows for rapid identification of high quality chemical starting points against the native, full-length protein in live cells.
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Primary screening with CETSA is a service that offers high-throughput screening of compound libraries . This method can measure and quantify the binding of compounds to their targets in live cells, in lead generation. enabling you to quickly identify the most promising hit compounds for the next stage of drug discovery. This approach can save time, money and reduce attrition rates in drug discovery.
With our primary screening with CETSA service, you can benefit from:
- Rapid assay development, without a need to engineer a cell line or to modify compounds
- High Throughput assay suitable even for challenging targets including non-enzymatic proteins or targets not amenable to purification
- Identification of high quality compound hits
Our primary screening service can be applied in the lead generation stage for rapid identification of novel chemical starting points.
