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Pyrintegrin

Integrin and tyrosine kinase activator; Activates Integrin, FGFR, IGFR and HER2

STEMCELL Technologies Inc.

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Pyrintegrin is a 2,4-disubstituted pyrimidine that induces the activation of β1 integrin and multiple growth factor receptors, including FGFR1, IGFR1, EGFR1, and HER2 (Xu et al.).

MAINTENANCE AND SELF-RENEWAL

  • Enhances integrin-dependent attachment and survival of human embryonic stem (ES) cells following trypsin-mediated single-cell dissociation (Xu et al.).

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