QCM Chemotaxis Cell Migration Assays
Chemotaxis assays are ideal for assessing the effects of pharmacological compounds on the motility of tumor cells, and for analyzing the migratory capacity of multiple cell lines in parallel. The format options enable large-scale screening and quantitative comparison of multiple samples in a user friendly, sensitive, HTS system. Quantitative fluorescent method increases sensitivity 10-fold over similar assays on the market…
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easy to use with reproducible results.
Review Date: 26 Jan 2011 | Merck
Chemotaxis assays are ideal for assessing the effects of pharmacological compounds on the motility of tumor cells, and for analyzing the migratory capacity of multiple cell lines in parallel. The format options enable large-scale screening and quantitative comparison of multiple samples in a user friendly, sensitive, HTS system.
- Quantitative fluorescent method increases sensitivity 10-fold over similar assays on the market
- Does not require cell pre-labeling, cell scraping, or cell counting
- Results in 4–24 hours
- 96-well plate is ideal for high throughput screening
QCM Chemotaxis Cell Migration Assays are built on the platform of a multiwell plate that includes a 24- or 96-well migration chamber and a feeder tray. Each chamber contains a microporous polycarbonate membrane of a specified pore size. Both sides of the membrane are uncoated. Cells of interest are pipetted onto the top of the insert. Migratory cells move through the pores of the membrane and cling to the bottom of the polycarbonate membrane, in response to a chemoattractant loaded into the bottom feeder tray.
