Rabbit anti-SARS-CoV-2 S1 RBD antibody

Antigen Information

Accession Number:

QHD43416

Protein Name & Synonyms:

SARS-CoV-2 S1RBD

Target Species:

Virus

Antibody Specifications

Applications:

ELISA (recommended work dilution = 1:160,000)

Host Species:

Rabbit

Preparation:

This antibody was produced from antiserum of rabbits immunized with a recombinant SARS-CoV-2 S1 RBD protein. The IgG fraction was purified by Protein A affinity chromatography.

Reconstitution:

Product is supplied as a powder obtained from lyophilization of purified antibody in 1X PBS, aliquot using ddH2O. Reconstitute the antibody with sterile water to a final concentration of 1 mg/ml.

Clonality:

Polyclonal

Description

It's been reported that 2019-nCoV (COVID-19) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Specificity

This antibody was selected for its ability to bind to the virus SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) from the disease COVID-19.

Storage

Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for at least 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C. Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.