Robust and pH stable process biochromatography material: YMC-Triart Prep Bio200 C8
Highly robust hybrid silica material for the purification of proteins, peptides and oligonucleotides, which combines mechanical strength and pH stability. The larger pore size makes YMC Triart-Prep Bio200 C8 the ideal choice for the purification of mid-size to large biomolecules.
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YMC-Triart Prep Bio200 C8 is especially designed for industrial-scale applications of larger peptides, specifically insulin, proteins, and oligonucleotides. This organic-inorganic hybrid silica-based material contains organic groups within the silicon dioxide network, making it more resistant to a wider pH range.
The innovative YMC-Triart Prep Bio200 C8 combines mechanical strength and pH stability which allows more flexibility for process development. It can be used in a pH range of 2.0 - 10.0 and allows efficient cleaning-in-place (CIP) procedures. YMC-Triart Prep Bio200 C8 provides good peak shapes even after 300 alkaline cleaning cycles!
Compared to traditional silica-based widepore C8 materials YMC-Triart Prep Bio200 C8 has been shown to have more than 3-fold longer lifetime. In addition it provides high loadability at low fraction volume which results in a higher productivity. The results mean improved production procedures and reduced overall costs.
YMC-Triart Prep Bio200 C8 Features:
- Mechanical stability
- Extended pH range
- CIP with NaOH solutions applicable
- More than 3-fold longer lifetimes
- Cost efficiency
- Available as packing material in multi-ton scale and in preparative columns
YMC-Triart Prep Bio200 C8 Characteristics:
- Modification: C8
- Particle size: 10 µm
- Pore size: 200 Å
- pH range: 2 - 10
- Separation modes: RP, SFC, SMB
