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RSC-133
Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)
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Reprogramming stimulating compound (RSC)-133 is an indole derivative that specifically inhibits DNA methyltransferase DNMT1 (Lee et al.).
REPROGRAMMING
- Increases kinetics and efficiency of reprogramming human foreskin fibroblasts to induced pluripotent stem cells, when used with reprogramming factors OCT4, SOX2, KLF4, and c-MYC (Lee et al.).
MAINTENANCE & SELF-RENEWAL
- Supports the maintenance of human pluripotent stem cells in unconditioned medium (Lee et al.).