Spike (SARS-CoV-2) Pseudotyped Lentivirus (eGFP Reporter)
The safe alternative to using live coronavirus
The supplier does not provide quotations for this product through SelectScience. You can search for similar products in our Product Directory.
Our Spike Pseudotyped Lentivirus offers a chance to study the mechanism of SARS-CoV-2 viral transduction, as well as screening for neutralizing antibodies and chemical compounds, when used in combination with ACE2 lentivirus. This lentivirus uses SARS-CoV-2 Spike protein (Genbank Accession #QHD43416.1) instead of VSV-G viral fusion protein as the envelope glycoprotein. Spike mediates the fusion between the viral envelopment and host cell membrane. These pseudovirions also contain the enhanced GFP gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be conveniently determined via eGFP activity. The SARS-CoV-2 Spike pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility.
