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Stauprimide
Inhibitor of NME2 localization; Suppresses c-MYC expression
Stauprimide
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Stauprimide specifically inhibits the nuclear localization of NME2, which results in the suppression of c-MYC - a key regulator of pluripotency - thereby priming cells for differentiation (Zhu et al.).
DIFFERENTIATION
- Enhances cytokine-mediated directed differentiation of mouse and human pluripotent stem cells to multiple lineages, including definitive endoderm, neural progenitors, and mesodermal derivatives such as cardiomyocytes (Zhu et al.; Tahamtani et al.).
