TOYOPEARL GigaCap® Ion Exchange Media
TOYOPEARL GigaCap® Series offers highest capacity for ion exchange purification steps
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Great results in a short development times
Purification
Product used in the polishing phase for the purification of a bispecific antibody. Excellent quality obtained in terms of purity and removal of endotoxins. Excellent value for money.
Review Date: 23 Aug 2023 | Tosoh Bioscience
Nice IEX resin
Preparative purification of recombinant proteins
The Toyopearl GigaCap S650-S resin has a high binding capacity for the tested proteins and showed additionally a good separation performance. Furthermore it showed a good stability to sodium hydroxide CIPs.
Review Date: 15 Aug 2023 | Tosoh Bioscience
Good quality and good prices.
Purification of biologics
The product delivers high purity yields. Usually, the achieved loading densities are in the same range as those of competitors' products. Packing is relatively easy.
Review Date: 10 Feb 2020 | Tosoh Bioscience
The matrix.
Development of protein purification processes
Compared to other products used for my specific application in the field of mAb purification, Toyopearl IEX-materials (650CM, 650S) were showing more gentle interactions with my molecule. This is most likely due to the methycrylat-matrix of the resin, where I am receiving less aggregated and multimerized mAb´s.
Review Date: 7 Feb 2020 | Tosoh Bioscience
TOYOPEARL GigaCap® Series offers highest capacity for ion exchange purification steps
TOYOPEARL GigaCap ion exchange resins were developed to meet the actual chromatographic needs in high throughput purification of monoclonal antibodies and other proteins. They combine excellent pressure flow characteristics and high chemical stability with high dynamic binding capacities and recoveries.
The TOYOPEARL GigaCap family provides two choices for both anion and cation exchange respectively:
- TOYOPEARL GigaCap S-650 is a strong cation exchange resin
- TOYOPEARL GigaCap CM-650M is a weak cation exchange resin
- TOYOPEARL GigaCap Q-650 is a strong anion exchange resin
- TOYOPEARL GigaCap DEAE-650M is a weak anion exchange resin
TOYOPEARL GigaCap Features:
- High binding capacities at short residence times
- Fast kinetics generating low elution pool volumes
- Excellent mechanical and chemical stability
- Superior pressure flow properties
