Twist High Throughput Antibody Production
High Throughput Antibody Production by Twist is a gene-to-protein workflow that relieves the costly bottleneck in discovery pipelines by producing tens to thousands of diverse antibodies for screening biophysical and pharmacokinetic properties. You submit the antibody sequence, and we’ll do the rest.
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Simple service delivered well
Drug delivery research
Simple to order, and the Twist Bioscience team were helpful and supportive with my queries. Their QC report was provided at the time of shipping, allowing us to prepare for arrival. The antibodies arrived safely on time. The yields were within the expected range.
Review Date: 12 Aug 2024 | Twist Bioscience
Great High-throughput antibody expression experience
Antibody discovery and engineering screening of hits
Twist high-throughput antibody services are great value with high quality deliverables. The combination of their wet-lab throughput as well as customer care team makes them a CRO of choice for us.
Review Date: 23 Jul 2024 | Twist Bioscience
There's no other antibody service like HT IgG
Outsourced transient expression of monoclonal antibodies
Twist's HT IgG service is a soup-to-nuts operation that should keep other CROs up at night. In our experience, turnaround time has been ±2 days from estimate (very reliable) and we've had constant R&D and technical support updates and responses to our questions (transparent, honest, and fast support). It's great to be able to go from a CSV file with your favorite amino acid or DNA sequences and have a single company take care of the vector synthesis and cloning and carry that product forward into transient expression of candidate antibodies. There's flexibility and reasonable price scaling for how much of a given set of antibodies you want (supernatants vs. purified, small vs. larger volumes, with or without buffer exchange) and how you want to receive them (vials, micronic plate, etc.). The master supply agreement is very reasonable and won't give you or your lawyers heartburn. I'm taking 1 star off of "ease of use" (wrote this review March 2023) because the CSV upload for sequences could be smoother and is a little painful to click through, and 1 star off of value for money because, well, DNA synthesis is expensive (I would rate comparable services a 2 or 3, Twist is the clear winner in my opinion here).
Review Date: 3 Mar 2023 | Twist Bioscience
Excellent and reliable IgG production service.
Therapeutic antibody discovery
Twist has excellent e-commerce system for ordering IgG synthesis. We chose 8 mL production scale that should yield in approx. 1 mg of the protein. Twist delivered the samples according to the service description, before the deadline. The shipment was easily trackable, with a lot of dry ice, samples were safe and frozen upon arrival. The production yield was around 0.7 mg for 3 IgGs, 0.5 mg for 1 IgG, and 0.4 mg for 1 IgG. I think this info may be valuable for experiment planning. We used the molecules for binding assays and epitope binning.
Review Date: 9 Jan 2023 | Twist Bioscience
High Throughput Antibody Production by Twist is a gene-to-protein workflow that relieves the costly bottleneck in discovery pipelines by producing tens to thousands of diverse antibodies for screening biophysical and pharmacokinetic properties. You submit the antibody sequence, and we’ll do the rest.
