Products & ReviewLife Sciences
Twist Universal Blockers
Twist Biosciencemethylation, genome
A single blocking solution for multiple adapter applications
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In targeted next-generation sequencing (NGS), a blocking solution is used during probe hybridization to prevent non-specific hybridization between target enrichment probes and adapter sequences. Twist Universal blockers are designed to block multiple TruSeq-compatible barcode sequences and adapter lengths. They can accommodate multiple projects and applications, eliminating the need to purchase multiple blocker products for TruSeq-compatible adapters with varied index designs.
KEY BENEFITS
Flexible Blocking Solution
- No need for adapter-specific blockers — blocks many different adapter designs
- Effective across singleplex and multiplex target enrichment workflows
- Improves on-target capture regardless of panel size
Improved On-Target Capture
- Prevents cross-hybridization between TruSeq-compatible adapters
- Enhances the performance of target enrichment workflows
Maximized Efficiency
- Ready-to-use formulation
- Reduces per-sample sequencing cost
