Wieslab® Complement Alternative Pathway (RUO & IVD*)
The Wieslab® Complement System Alternative Pathway kit, available as IVD* and RUO, is a high-precision assay for detecting alternative complement pathway activity in human serum, the RUO is also suitable for primates and porcine samples. It uses ELISA technology with specific detection of C5b-9 for accurate results, offering advantages over traditional assays. *Subject to local registration.
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The Wieslab® Complement System Alternative Pathway kit is an enzyme immunoassay for the qualitative determination of functional alternative complement pathway and determination of complement deficiencies in human serum. Non-human primate and swine samples can also be assayed with Wieslab® Complement System Alternative pathway.
The Wieslab Complement assay combines tthe specific activation of the pathway with the use of labeled antibodies specific for a neoepitope of the terminal complement complex, C5b-9, produced as the result of complement activation. The amount of C5b-9 generated is proportional to the functional activity of the complement system. The convenient ELISA technology has several advantages compared to the traditional hemolytic assays.
The WieslabComplement assays have been published as useful tools in evaluation of complement therapeutics, in clinic, clinical trials and in drug development.
