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(Z)-4-Hydroxytamoxifen

Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor

STEMCELL Technologies Inc.

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(Z)-4-Hydroxytamoxifen is a cell-permeable selective estrogen receptor modulator (SERM) that binds to estrogen receptors (ER) and estrogen-related receptors (ERR) with both estrogenic and anti-estrogenic effects (Poulin et al.).

CANCER RESEARCH

  • Suppresses tumor growth in breast cancer cells (Freiss et al.; Osborne et al.).

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