Products & ReviewLife Sciences

ZL41 Cell sCMOS

Oxford Instruments AndorAvailable: Worldwide

ZL41 Cell is a new addition to the Zyla sCMOS series, designed specifically for life science researchers. It offers exceptional imaging flexibility, value, and compatibility. ZL41 Cell 4.2 is an upgrade from the Zyla 4.2 PLUS, delivering up to 82% QEmax and sub-electron read noise, making it ideal for applications that require optimal sensitivity and speed.

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ZL41 Cell 5.5 replaces the Zyla 5.5 and offers a 22 mm format sensor with 64% QE. It has a Global Shutter mode that is perfect for snapshot imaging of fast-moving objects without temporal distortion. The camera also features SRRF-Stream+, LightScan PLUS, and FCS Mode, making it a versatile and cost-effective solution for life science imaging.

GPU Express simplifies and optimises data transfer from the camera, making it ideal for data-intensive imaging experiments. The Camera Link version offers up to a blistering 100 fps, while the USB 3.0 interface offers 53 fps with the industry's fastest Region of Interest (ROI) frame rates. The camera offers industry-leading linearity (99.8%) for unparalleled quantitative accuracy of measurement across the full dynamic range.

Finally, the all-new sensor chamber design provides greater robustness and longevity, with a 3-year chamber integrity warranty. The ZL41 Cell models share software compatibility with the previous editions of Zyla 4.2P and 5.5 models.

ZL41 Cell sCMOS Features:

  • Up to 82% QE - Highest and broadest available sCMOS QE. Optimized to a wide range of common fluorophores. Enables shorter exposures, faster frame rates and reduced photobleaching.
  • 0.9 e- read noise- Lowest read noise sCMOS. Significantly lower than any CCD.
  • Industry Fastest Frame Rates- Follow faster processes. Industry-fastest USB 3.0 frame rates, 53 fps (full frame). 100 fps (full frame) sustained via Camera Link.
  • 4.2 and 5.5 megapixel sensor formats and 6.5 µm pixels - - Delivers extremely sharp resolution for modern microscopes with C-mount ports.
  • SRRF-Stream+ - Super Resolution made cost effective, flexible and easy. - New ZL41 Cell 4.2 compatible with our real-time Super-resolution Technology.
  • LightScan PLUS - - Reduce background and improve contrast and resolution in scattering samples. Designed to allow users to optimise signal strength and confocality concurrently in applications such as Scanned Light Sheet Microscopy and Line Scanning Confocal Microscopy.
  • FCS Mode - - Obtain the fastest speeds from minimal height ROIs configured for Fluorescence Correlation Spectroscopy experiments
  • GPU Express- Simplify and optimize data transfers from camera to a CUDA-enabled NVidia Graphical Processing Unit (GPU) card to facilitate accelerated GPU processing as part of the acquisition pipeline
  • Compatible- Maintains compatibility with previous Zyla series with no changes at EEPROM level.
  • Robust - - New mechanical design for greater longevity and sensor protection. 3 years warranty on sensor chamber integrity.
  • Ultra - Low Fan Vibration - - Designed with vibration sensitive experiments in mind, such as super-resolution microscopy.
  • Dual-Gain Amplifiers - - Maximum well depth and lowest noise simultaneously, affording extended dynamic range of 33,000:1
  • 12-bit and 16-bit modes- 12-bit for absolute fastest frame rates through USB 3.0; 16-bit for full dynamic range.
  • Extensive FPGA on-head data processing - - Essential to ensure best image quality and quantitative fidelity from sCMOS technology.
  • Hardware Timestamp - - FPGA generated timestamp with 25ns accuracy.
  • Dynamic Baseline Clamp - - Essential to ensure quantitative accuracy across the image area and between successive images of a kinetic series.
  • Python Ready - - Take control with our new python integrated SDK. Ideal for custom system integrations.
  • Water Cooled Option- Option for vibration sensitive applications. Available under request

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